Dysferlin Interacts with Affixin (β-Parvin) at the Sarcolemma
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چکیده
منابع مشابه
Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair
Failure to repair the sarcolemma leads to muscle cell death, depletion of stem cells and myopathy. Hence, membrane lesions are instantly sealed by a repair patch consisting of lipids and proteins. It has remained elusive how this patch is removed to restore cell membrane integrity. Here we examine sarcolemmal repair in live zebrafish embryos by real-time imaging. Macrophages remove the patch. P...
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The corresponding author, Michael Sinnreich, has requested retraction of this article because the data used in this study were found to have been manipulated, and the integrity of the study to be compromised. The following issues were specified: Images in Figures 1B and 3C had been duplicated; Western blot images in Figure 2B (2nd row, NiNTA pulldown, IB: anti-FLAG) were found to be manipulated...
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Leukocyte extravasation is an important step of inflammation, in which integrins have been demonstrated to play an essential role by mediating the interaction of leukocytes with the vascular endothelium and the subendothelial extracellular matrix. Previously, we identified an integrin-linked kinase (ILK)-binding protein affixin (beta-parvin), which links initial integrin signals to rapid actin ...
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ژورنال
عنوان ژورنال: Journal of Neuropathology & Experimental Neurology
سال: 2005
ISSN: 0022-3069,1554-6578
DOI: 10.1093/jnen/64.4.334